Sodium ion → [2-(3-Methylphenyl)-quinazolin-4-yl]-(5-methyl-2H-pyrazol-3-yl)-amine

HRID 936677Notes

Reaction equation

HRID 936677 reaction equation
[C:29](=[O:30])([O-:31])[O-:32].[C:35]([P:36]([C:37]([CH3:38])([CH3:39])[CH3:40])[C:41]([CH3:42])([CH3:43])[CH3:44])([CH3:45])([CH3:46])[CH3:47].[Cl:1][c:2]1[n:3][c:4]2[cH:5][cH:6][cH:7][cH:8][c:9]2[c:10]([NH:12][c:13]2[n:14][nH:15][c:16]([CH3:18])[cH:17]2)[n:11]1.[Na+:33].[Na+:34].[O:48]=[CH:49][N:50]([CH3:51])[CH3:52].[c:19]1([CH3:28])[cH:20][c:21]([B:25]([OH:26])[OH:27])[cH:22][cH:23][cH:24]1>>[c:2]1(-[c:21]2[cH:20][c:19]([CH3:28])[cH:24][cH:23][cH:22]2)[n:3][c:4]2[cH:5][cH:6][cH:7][cH:8][c:9]2[c:10]([NH:12][c:13]2[nH:14][n:15][c:16]([CH3:18])[cH:17]2)[n:11]1

Participants

7

Reactant 6

HCID 923Sodium ion2×HCID 6228DimethylformamideHCID 19660Carbonate IonHCID 83681Tris(1,1-dimethylethyl)phosphineHCID 27339503-Tolylboronic acidHCID 219391632-Chloro-n-(5-methyl-1h-pyrazol-3-yl)quinazolin-4-amine

Product 1

HCID 178419088[2-(3-Methylphenyl)-quinazolin-4-yl]-(5-methyl-2H-pyrazol-3-yl)-amine

Sources & evidence

ORD record
ord-fc17ba9907c34aa396206f4ea3b19648
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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