Tetrahydrofuran → (3-Chloro-1-benzothien-2-yl)methanol

HRID 936848Notes

Reaction equation

HRID 936848 reaction equation
[Al+3:15].[CH2:20]1[O:21][CH2:22][CH2:23][CH2:24]1.[Cl:1][c:2]1[c:3]2[c:4]([s:5][c:6]1[C:7](=[O:8])[OH:9])[cH:10][cH:11][cH:12][cH:13]2.[H-:14].[H-:17].[H-:18].[H-:19].[Li+:16]>>[Cl:1][c:2]1[c:3]2[c:4]([s:5][c:6]1[CH2:7][OH:8])[cH:10][cH:11][cH:12][cH:13]2

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 104727Aluminum CationHCID 166653Hydride4×HCID 3079643-Chloro-1-benzothiophene-2-carboxylic acid

Product 1

HCID 821965(3-Chloro-1-benzothien-2-yl)methanol

Sources & evidence

ORD record
ord-66417a369932466e8dce045c36eed8d2
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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