Hydrochloric Acid → 3-Bromo-2-fluoro-5-methylaniline

HRID 937068Notes

Reaction equation

HRID 937068 reaction equation
[Br:1][c:2]1[c:3]([F:17])[c:4]([NH:9][C:10](=[O:11])[O:12][C:13]([CH3:14])([CH3:15])[CH3:16])[cH:5][c:6]([CH3:8])[cH:7]1.[CH:21]([OH:22])([CH3:23])[CH3:24].[ClH:18].[Na+:20].[OH-:19].[OH2:25]>>[Br:1][c:2]1[c:3]([F:17])[c:4]([NH2:9])[cH:5][c:6]([CH3:8])[cH:7]1

Participants

7

Reactant 6

HCID 313Hydrochloric AcidHCID 923Sodium ionHCID 961HydroxideHCID 962WaterHCID 3776IsopropanolHCID 69811922Tert-butyl 3-bromo-2-fluoro-5-methylphenylcarbamate

Product 1

HCID 670534843-Bromo-2-fluoro-5-methylaniline

Sources & evidence

ORD record
ord-77266279af21409eab96725971892466
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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