Tetrahydrofuran → (RS)-1-[(3RS,4SR)-1-benzyl-4-(3,4-dichloro-phenyl)-pyrrolidin-3-yl]-propan-1-ol

HRID 937354Notes

Reaction equation

[Al+3:26].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH:10]([C:21]([CH2:22][CH3:23])=[O:24])[CH:11]([c:13]2[cH:14][c:15]([Cl:20])[c:16]([Cl:19])[cH:17][cH:18]2)[CH2:12]1.[CH2:31]1[O:32][CH2:33][CH2:34][CH2:35]1.[H-:25].[H-:28].[H-:29].[H-:30].[Li+:27]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH:10]([CH:21]([CH2:22][CH3:23])[OH:24])[CH:11]([c:13]2[cH:14][c:15]([Cl:20])[c:16]([Cl:19])[cH:17][cH:18]2)[CH2:12]1