Dimethylformamide → Tert-butyl 6-formylchroman-4-ylcarbamate

HRID 937430Notes

Reaction equation

HRID 937430 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][CH:8]1[CH2:9][CH2:10][O:11][c:12]2[cH:13][cH:14][c:15]([Br:18])[cH:16][c:17]21)=[O:19].[CH2:20]([Li:21])[CH2:22][CH2:23][CH3:24].[CH2:30]1[O:31][CH2:32][CH2:33][CH2:34]1.[O:25]=[CH:26][N:27]([CH3:28])[CH3:29]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][CH:8]1[CH2:9][CH2:10][O:11][c:12]2[cH:13][cH:14][c:15]([CH:26]=[O:25])[cH:16][c:17]21)=[O:19]

Participants

5

Reactant 4

HCID 6228DimethylformamideHCID 8028TetrahydrofuranHCID 68930912HCID 68930912, compoundHCID 178418339Butyllithium

Product 1

HCID 86598502Tert-butyl 6-formylchroman-4-ylcarbamate

Sources & evidence

ORD record
ord-9fc3cffc83d44ec493080e7e06b55197
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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