Water → 1-[2-Nitro-4-(trifluoromethyl)phenyl]piperidine
Reaction equation
[CH2:1]1[CH2:2][CH2:3][NH:4][CH2:5][CH2:6]1.[CH3:7][N:8]([CH3:9])[CH:10]=[O:11].[Cl:12][c:13]1[c:14]([N+:23](=[O:24])[O-:25])[cH:15][c:16]([C:19]([F:20])([F:21])[F:22])[cH:17][cH:18]1.[OH2:26]>>[CH2:1]1[CH2:2][CH2:3][N:4]([c:13]2[c:14]([N+:23](=[O:24])[O-:25])[cH:15][c:16]([C:19]([F:20])([F:21])[F:22])[cH:17][cH:18]2)[CH2:5][CH2:6]1Participants
5
Sources & evidence
- ORD record
- ord-ce2d0fbf2a214b5e851037d97acc2907
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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