Dimethylformamide → Methyl 5'-(3-furoylamino)-2'-methyl-1,1'-biphenyl-4-carboxylate
Reaction equation
[CH:75]([N:76]([CH2:77][CH3:78])[CH:79]([CH3:80])[CH3:81])([CH3:82])[CH3:83].[NH2:57][c:58]1[cH:59][cH:60][c:61]([CH3:74])[c:62](-[c:64]2[cH:65][cH:66][c:67]([C:70](=[O:71])[O:72][CH3:73])[cH:68][cH:69]2)[cH:63]1.[O:84]=[CH:85][N:86]([CH3:87])[CH3:88].[OH:1][C:2](=[O:3])[c:4]1[cH:5][cH:6][o:7][cH:8]1.[P-:33]([F:34])([F:35])([F:36])([F:37])([F:38])[F:39].[P-:9]([F:10])([F:11])([F:12])([F:13])([F:14])[F:15].[n:16]1([O:17][C:18]([N:19]([CH3:20])[CH3:21])=[N+:22]([CH3:23])[CH3:24])[c:25]2[n:26][cH:27][cH:28][cH:29][c:30]2[n:31][n:32]1.[n:40]1([O:41][C:42]([N:43]([CH3:44])[CH3:45])=[N+:46]([CH3:47])[CH3:48])[c:49]2[cH:50][cH:51][cH:52][cH:53][c:54]2[n:55][n:56]1>>[C:2](=[O:3])([c:4]1[cH:5][cH:6][o:7][cH:8]1)[NH:57][c:58]1[cH:59][cH:60][c:61]([CH3:74])[c:62](-[c:64]2[cH:65][cH:66][c:67]([C:70](=[O:71])[O:72][CH3:73])[cH:68][cH:69]2)[cH:63]1Participants
8
Reactant 7
HCID 6228Dimethylformamide
HCID 9886Hexafluorophosphate2×
HCID 102683-Furoic acid
HCID 81531Diisopropylethylamine
HCID 130500O-benzotriazol-1-yl-tetramethyluronium
HCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminium
HCID 21090583Methyl 5'-amino-2'-methyl-1,1'-biphenyl-4-carboxylateProduct 1
Sources & evidence
- ORD record
- ord-af4e410aab724eb7a222f9832ba20e93
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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