Hydrochloric Acid → 4-hydroxy-2H-naphtho[2,1-e]-1,2thiazine-3-carboxylic acid methyl ester-1,1-dioxide

HRID 937724Notes

Reaction equation

HRID 937724 reaction equation
[C:23]([OH:24])([CH3:25])([CH3:26])[CH3:27].[CH3:29][OH:30].[CH3:2][O:3][C:4]([CH2:5][N:6]1[S:7](=[O:20])(=[O:21])[c:8]2[c:9]([cH:12][cH:13][c:14]3[cH:15][cH:16][cH:17][cH:18][c:19]23)[C:10]1=[O:11])=[O:22].[ClH:28].[Na:1]>>[CH3:2][O:3][C:4]([C:5]1=[C:10]([OH:11])[c:9]2[c:8]([c:19]3[c:14]([cH:13][cH:12]2)[cH:15][cH:16][cH:17][cH:18]3)[S:7](=[O:20])(=[O:21])[NH:6]1)=[O:22]

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 887MethanolHCID 6386tert-ButanolHCID 5360545SodiumHCID 105426033-Oxo-naphth[2,1-d]isothiazoline-2-acetic acid methyl ester-1,1-dioxide

Product 1

HCID 547193904-hydroxy-2H-naphtho[2,1-e]-1,2thiazine-3-carboxylic acid methyl ester-1,1-dioxide

Sources & evidence

ORD record
ord-25b221a017594e0a8a9ae30d0e5da68a
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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