Tetrahydrofuran → 5-Chloro-2-methylbenzylamine

HRID 937962Notes

Reaction equation

HRID 937962 reaction equation
[Al+3:12].[CH2:17]1[O:18][CH2:19][CH2:20][CH2:21]1.[CH3:1][c:2]1[c:3]([C:4]#[N:5])[cH:6][c:7]([Cl:10])[cH:8][cH:9]1.[H-:11].[H-:14].[H-:15].[H-:16].[Li+:13]>>[CH3:1][c:2]1[c:3]([CH2:4][NH2:5])[cH:6][c:7]([Cl:10])[cH:8][cH:9]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 104727Aluminum CationHCID 1427435-Chloro-2-methylbenzonitrileHCID 166653Hydride4×

Product 1

HCID 27576735-Chloro-2-methylbenzylamine

Sources & evidence

ORD record
ord-7179f2fc48f64eb59323ee6ffc0592b7
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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