Hydrochloric Acid → N-(7-(2-Fluoro-4-iodophenylamino)-8-fluoro-4-methylquinazolin-6-yl)-1-(2-hydroxyethyl)cyclopropane-1-sulfonamide
Reaction equation
[CH2:40]1[O:41][CH2:42][CH2:43][CH2:44]1.[ClH:39].[F:1][c:2]1[c:3]([NH:9][c:10]2[c:11]([NH:22][S:23](=[O:24])(=[O:25])[C:26]3([CH2:29][CH2:30][O:31][Si:32]([C:33]([CH3:34])([CH3:35])[CH3:36])([CH3:37])[CH3:38])[CH2:27][CH2:28]3)[cH:12][c:13]3[c:14]([CH3:21])[n:15][cH:16][n:17][c:18]3[c:19]2[F:20])[cH:4][cH:5][c:6]([I:8])[cH:7]1>>[F:1][c:2]1[c:3]([NH:9][c:10]2[c:11]([NH:22][S:23](=[O:24])(=[O:25])[C:26]3([CH2:29][CH2:30][OH:31])[CH2:27][CH2:28]3)[cH:12][c:13]3[c:14]([CH3:21])[n:15][cH:16][n:17][c:18]3[c:19]2[F:20])[cH:4][cH:5][c:6]([I:8])[cH:7]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-75be6217b02d40a8abd1ac95f63a9113
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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