Chloride → 4-Chloro-1-[4-fluoro-2-(methylsulfanyl)phenyl]-1-butanone

HRID 938303Notes

Reaction equation

HRID 938303 reaction equation
[Al+3:18].[Cl-:17].[Cl-:19].[Cl-:20].[Cl:10][CH2:11][CH2:12][CH2:13][C:14](=[O:15])[Cl:16].[Cl:21][CH2:22][Cl:23].[F:1][c:2]1[cH:3][c:4]([S:8][CH3:9])[cH:5][cH:6][cH:7]1>>[F:1][c:2]1[cH:3][c:4]([S:8][CH3:9])[c:5]([C:14]([CH2:13][CH2:12][CH2:11][Cl:10])=[O:15])[cH:6][cH:7]1

Participants

6

Reactant 5

HCID 312Chloride3×HCID 6344DichloromethaneHCID 783704-Chlorobutyryl chlorideHCID 104727Aluminum CationHCID 27591643-Fluorothioanisole

Product 1

HCID 227354674-Chloro-1-[4-fluoro-2-(methylsulfanyl)phenyl]-1-butanone

Sources & evidence

ORD record
ord-d0ba190a726547e1a2ffeb7bebf907a9
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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