Hydrochloric Acid → 5-fluoro-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole
Reaction equation
[CH3:22][OH:23].[ClH:20].[F:3][c:4]1[cH:5][c:6]2[cH:7][cH:8][nH:9][c:10]2[cH:11][cH:12]1.[K+:2].[NH:13]1[CH2:14][CH2:15][C:16](=[O:19])[CH2:17][CH2:18]1.[OH-:1].[OH2:21].[OH2:24]>>[F:3][c:4]1[cH:5][c:6]2[c:7]([C:16]3=[CH:15][CH2:14][NH:13][CH2:18][CH2:17]3)[cH:8][nH:9][c:10]2[cH:11][cH:12]1Participants
8
Sources & evidence
- ORD record
- ord-a0a35fe5858d47ad846d62eda5b7cb00
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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