Tetrahydrofuran → tert-butyl 4-[N'-(2-methoxyphenyl)ureido]-3-methylphenylacetate

HRID 938558Notes

Reaction equation

HRID 938558 reaction equation
[CH2:35]1[O:36][CH2:37][CH2:38][CH2:39]1.[CH3:17][CH2:18][N:19]([CH2:20][CH3:21])[CH2:22][CH3:23].[CH3:24][O:25][c:26]1[c:27]([N:32]=[C:33]=[O:34])[cH:28][cH:29][cH:30][cH:31]1.[NH2:1][c:2]1[c:3]([CH3:16])[cH:4][c:5]([CH2:8][C:9](=[O:10])[O:11][C:12]([CH3:13])([CH3:14])[CH3:15])[cH:6][cH:7]1>>[NH:1]([c:2]1[c:3]([CH3:16])[cH:4][c:5]([CH2:8][C:9](=[O:10])[O:11][C:12]([CH3:13])([CH3:14])[CH3:15])[cH:6][cH:7]1)[C:33]([NH:32][c:27]1[c:26]([O:25][CH3:24])[cH:31][cH:30][cH:29][cH:28]1)=[O:34]

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 8471TriethylamineHCID 69695Benzene, 1-isocyanato-2-methoxy-HCID 23512173Tert-butyl 4-amino-3-methylphenylacetate

Product 1

HCID 23512525tert-butyl 4-[N'-(2-methoxyphenyl)ureido]-3-methylphenylacetate

Sources & evidence

ORD record
ord-fca7aefcc35c4adcb087037a37dbd0f9
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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