Acetone → N-propyl-3-(m-trifluoromethylphenyl)-piperidine
Reaction equation
[Ag:25]=[O:26].[CH2:17]([CH2:18][CH3:19])[I:20].[CH3:21][C:22](=[O:23])[CH3:24].[F:1][C:2]([c:3]1[cH:4][c:5]([CH:9]2[CH2:10][NH:11][CH2:12][CH2:13][CH2:14]2)[cH:6][cH:7][cH:8]1)([F:15])[F:16]>>[F:1][C:2]([c:3]1[cH:4][c:5]([CH:9]2[CH2:10][N:11]([CH2:17][CH2:18][CH3:19])[CH2:12][CH2:13][CH2:14]2)[cH:6][cH:7][cH:8]1)([F:15])[F:16]Participants
5
Sources & evidence
- ORD record
- ord-baf5388084654c28aa10c3de4c3320f4
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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