Dimethylformamide → 6-(4-Chloro-benzoyl)-4-(3-chloro-phenyl)-1-cyclopropylmethyl-1H-quinolin-2-one

HRID 939047Notes

Reaction equation

HRID 939047 reaction equation
[Br:34][CH2:35][CH:36]1[CH2:37][CH2:38]1.[C:28](=[O:29])([O-:30])[O-:31].[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:6](=[O:7])[c:8]2[cH:9][c:10]3[c:11](-[c:19]4[cH:20][c:21]([Cl:25])[cH:22][cH:23][cH:24]4)[cH:12][c:13](=[O:18])[nH:14][c:15]3[cH:16][cH:17]2)[cH:26][cH:27]1.[Cl:44][CH2:45][Cl:46].[Cs+:32].[Cs+:33].[O:39]=[CH:40][N:41]([CH3:42])[CH3:43]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:6](=[O:7])[c:8]2[cH:9][c:10]3[c:11](-[c:19]4[cH:20][c:21]([Cl:25])[cH:22][cH:23][cH:24]4)[cH:12][c:13](=[O:18])[n:14]([CH2:35][CH:36]4[CH2:37][CH2:38]4)[c:15]3[cH:16][cH:17]2)[cH:26][cH:27]1

Participants

7

Reactant 6

HCID 6228DimethylformamideHCID 6344DichloromethaneHCID 19660Carbonate IonHCID 81503BromomethylcyclopropaneHCID 104967Cesium cation2×HCID 155243306-(4-chlorobenzoyl)-4-(3-chlorophenyl)-2(1H)-quinolinone

Product 1

HCID 183790236-(4-Chloro-benzoyl)-4-(3-chloro-phenyl)-1-cyclopropylmethyl-1H-quinolin-2-one

Sources & evidence

ORD record
ord-35aaaed1529749caae74bae201ae51b7
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…