Ammonium → 4-[2,2,2-Trifluoro-1-(triethylsilyloxy)ethyl]pyridine
Reaction equation
[CH2:13]([CH3:14])[Si:15]([CH2:16][CH3:17])([CH2:18][CH3:19])[Cl:20].[CH3:23][N:24]([CH3:25])[c:26]1[cH:27][cH:28][n:29][cH:30][cH:31]1.[Cl-:21].[F:1][C:2]([CH:3]([OH:4])[c:5]1[cH:6][cH:7][n:8][cH:9][cH:10]1)([F:11])[F:12].[NH4+:22].[cH:32]1[cH:33][cH:34][n:35][cH:36][cH:37]1>>[F:1][C:2]([CH:3]([O:4][Si:15]([CH2:13][CH3:14])([CH2:16][CH3:17])[CH2:18][CH3:19])[c:5]1[cH:6][cH:7][n:8][cH:9][cH:10]1)([F:11])[F:12]Participants
7
Sources & evidence
- ORD record
- ord-ccf9b2328e984f6fa83b3f898203a42b
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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