HRID939641

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6228

N,N-Dimethylformamide

C3H7NO

HCID15908

1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimide

C8H17N3

HCID75771

1-Hydroxybenzotriazole

C6H5N3O

HCID58817250

未命名化合物

HCID68491438

未命名化合物

PRODUCTS

生成物

结构：Nc1ccccc1NC(=O)c1ccc(CNC(=O)C(=Cc2ccc(F)c(F)c2)c2ccc(F)cc2)cc1

HCID68492418

未命名化合物

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-32d182bc221441688147655a8abefb35
来源数据集: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D
来源说明: Validation data from https://doi.org/10.1039/C8SC04228D

反应 SMILES

[CH3:21][CH2:22][N:23]=[C:24]=[N:25][CH2:26][CH2:27][CH2:28][N:29]([CH3:30])[CH3:31].[F:1][c:2]1[cH:3][c:4]([CH:9]=[C:10]([C:11](=[O:12])[OH:13])[c:14]2[cH:15][cH:16][c:17]([F:20])[cH:18][cH:19]2)[cH:5][cH:6][c:7]1[F:8].[NH2:42][CH2:43][c:44]1[cH:45][cH:46][c:47]([C:48](=[O:49])[NH:50][c:51]2[c:52]([NH2:57])[cH:53][cH:54][cH:55][cH:56]2)[cH:58][cH:59]1.[O:60]=[CH:61][N:62]([CH3:63])[CH3:64].[OH:32][n:33]1[c:34]2[c:35]([cH:36][cH:37][cH:38][cH:39]2)[n:40][n:41]1>>[F:1][c:2]1[cH:3][c:4]([CH:9]=[C:10]([C:11](=[O:13])[NH:42][CH2:43][c:44]2[cH:45][cH:46][c:47]([C:48](=[O:49])[NH:50][c:51]3[c:52]([NH2:57])[cH:53][cH:54][cH:55][cH:56]3)[cH:58][cH:59]2)[c:14]2[cH:15][cH:16][c:17]([F:20])[cH:18][cH:19]2)[cH:5][cH:6][c:7]1[F:8]