Dichloromethane → Perfluorophenyl 2-cyanoacetate

HRID 939863Notes

Reaction equation

HRID 939863 reaction equation
[C:1](#[N:2])[CH2:3][C:4](=[O:5])[OH:6].[CH:7]1([N:8]=[C:9]=[N:10][CH:11]2[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16]2)[CH2:17][CH2:18][CH2:19][CH2:20][CH2:21]1.[Cl:34][CH2:35][Cl:36].[F:22][c:23]1[c:24]([F:33])[c:25]([F:32])[c:26]([F:31])[c:27]([F:30])[c:28]1[OH:29]>>[C:1](#[N:2])[CH2:3][C:4]([O:5][c:28]1[c:23]([F:22])[c:24]([F:33])[c:25]([F:32])[c:26]([F:31])[c:27]1[F:30])=[O:6]

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 9740Cyanoacetic acidHCID 10868DicyclohexylcarbodiimideHCID 13041Pentafluorophenol

Product 1

HCID 20402415Perfluorophenyl 2-cyanoacetate

Sources & evidence

ORD record
ord-590930dadba34480bfb014a656d6629e
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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