Sodium ion → 4-(3-Acetylamino-phenylamino)-piperidine-1-carboxylic acid tert-butyl ester

HRID 939940Notes

Reaction equation

HRID 939940 reaction equation
[C:12]([CH3:13])([CH3:14])([CH3:15])[O:16][C:17](=[O:18])[N:19]1[CH2:20][CH2:21][C:22](=[O:25])[CH2:23][CH2:24]1.[C:26]([BH3-:27])#[N:28].[CH:30]([OH:31])([CH3:32])[CH3:33].[NH2:1][c:2]1[cH:3][c:4]([NH:8][C:9]([CH3:10])=[O:11])[cH:5][cH:6][cH:7]1.[Na+:29]>>[NH:1]([c:2]1[cH:3][c:4]([NH:8][C:9]([CH3:10])=[O:11])[cH:5][cH:6][cH:7]1)[CH:22]1[CH2:21][CH2:20][N:19]([C:17]([O:16][C:12]([CH3:13])([CH3:14])[CH3:15])=[O:18])[CH2:24][CH2:23]1

Participants

6

Reactant 5

HCID 923Sodium ionHCID 3776IsopropanolHCID 7604m-AminoacetanilideHCID 498716Cyano-borohydrideHCID 735900tert-Butyl 4-oxopiperidine-1-carboxylate

Product 1

HCID 674007394-(3-Acetylamino-phenylamino)-piperidine-1-carboxylic acid tert-butyl ester

Sources & evidence

ORD record
ord-ed4a28c60eda410799f5b0b06548f7b1
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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