HRID940118

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6212

Chloroform

CHCl3

HCID8471

Triethylamine

C6H15N

HCID94429

Triphosgene

C3Cl6O3

HCID19896985

1-(1,3-Thiazol-2-yl)ethan-1-amine

C5H8N2S

HCID21891031

4-[(6,7-Dimethoxyquinolin-4-yl)oxy]-2-methoxyaniline

C18H18N2O4

PRODUCTS

生成物

结构：COc1cc(Oc2ccnc3cc(OC)c(OC)cc23)ccc1NC(=O)NC(C)c1nccs1

HCID9869779

1-[4-(6,7-Dimethoxyquinolin-4-yl)oxy-2-methoxyphenyl]-3-[1-(1,3-thiazol-2-yl)ethyl]urea

C24H24N4O5S

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-d14e4cccdda0478d8f938999e5a12649
来源数据集: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D
来源说明: Validation data from https://doi.org/10.1039/C8SC04228D

反应 SMILES

[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:6]([O:15][c:16]3[cH:17][c:18]([O:23][CH3:24])[c:19]([NH2:20])[cH:21][cH:22]3)[cH:7][cH:8][n:9][c:10]2[cH:11][c:12]1[O:13][CH3:14].[CH3:25][CH2:26][N:27]([CH2:28][CH3:29])[CH2:30][CH3:31].[CH:52]([Cl:53])([Cl:54])[Cl:55].[Cl:32][C:33]([Cl:34])([O:35][C:36]([O:37][C:38]([Cl:39])([Cl:40])[Cl:41])=[O:42])[Cl:43].[s:44]1[c:45]([CH:49]([CH3:50])[NH2:51])[n:46][cH:47][cH:48]1>>[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:6]([O:15][c:16]3[cH:17][c:18]([O:23][CH3:24])[c:19]([NH:20][C:36](=[O:42])[NH:51][CH:49]([c:45]4[s:44][cH:48][cH:47][n:46]4)[CH3:50])[cH:21][cH:22]3)[cH:7][cH:8][n:9][c:10]2[cH:11][c:12]1[O:13][CH3:14]