Acetic Acid → 4-{[(2,4-Dichloro-thiazol-5-yl)methyl]-isobutyl-amino}-piperidine-1-carboxylic acid t-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([NH:14][CH2:15][CH:16]([CH3:17])[CH3:18])[CH2:12][CH2:13]1.[CH3:28][C:29](=[O:30])[OH:31].[CH3:33][N:34]([CH3:35])[CH:36]=[O:37].[CH3:38][CH2:39][O:40][C:41](=[O:42])[CH3:43].[Cl:19][c:20]1[s:21][c:22]([CH:26]=[O:27])[c:23]([Cl:25])[n:24]1.[OH2:32]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([N:14]([CH2:15][CH:16]([CH3:17])[CH3:18])[CH2:26][c:22]2[s:21][c:20]([Cl:19])[n:24][c:23]2[Cl:25])[CH2:12][CH2:13]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-b038f09643b74a5e95030bd3c624dcb9
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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