1,2-Dichloroethane → 6-(3,4-Dimethoxyphenyl)-4-(4-mesylaminophenylamino)-2-methylpyrimidine

HRID 940251Notes

Reaction equation

HRID 940251 reaction equation
[CH3:26][S:27]([Cl:28])(=[O:29])=[O:30].[CH3:31][CH2:32][N:33]([CH2:34][CH3:35])[CH2:36][CH3:37].[CH:38]([Cl:39])([Cl:40])[Cl:41].[Cl:42][CH2:43][CH2:44][Cl:45].[NH2:1][c:2]1[cH:3][cH:4][c:5]([NH:8][c:9]2[n:10][c:11]([CH3:25])[n:12][c:13](-[c:15]3[cH:16][c:17]([O:23][CH3:24])[c:18]([O:21][CH3:22])[cH:19][cH:20]3)[cH:14]2)[cH:6][cH:7]1>>[NH:1]([c:2]1[cH:3][cH:4][c:5]([NH:8][c:9]2[n:10][c:11]([CH3:25])[n:12][c:13](-[c:15]3[cH:16][c:17]([O:23][CH3:24])[c:18]([O:21][CH3:22])[cH:19][cH:20]3)[cH:14]2)[cH:6][cH:7]1)[S:27]([CH3:26])(=[O:29])=[O:30]

Participants

6

Reactant 5

HCID 111,2-DichloroethaneHCID 6212ChloroformHCID 8471TriethylamineHCID 31297Methanesulfonyl chlorideHCID 201522544-(4-Aminophenylamino)-6-(3,4-dimethoxyphenyl)-2-methylpyrimidine

Product 1

HCID 201522626-(3,4-Dimethoxyphenyl)-4-(4-mesylaminophenylamino)-2-methylpyrimidine

Sources & evidence

ORD record
ord-abdd84455dbf41e693c73f68cadadde8
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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