4-Methoxybenzenesulfonyl chloride → N1-(cyclohexyloxy)-4-methoxy-1-benzenesulfonamide

HRID 940534Notes

Reaction equation

HRID 940534 reaction equation
[CH2:42]1[O:43][CH2:44][CH2:45][CH2:46]1.[CH3:21][O:22][c:23]1[cH:24][cH:25][c:26]([S:29](=[O:30])(=[O:31])[Cl:32])[cH:27][cH:28]1.[CH:1]1([O:7][N:8]2[C:9](=[O:10])[c:11]3[c:12]([cH:13][cH:14][cH:15][cH:16]3)[C:17]2=[O:18])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1.[CH:33]([N:34]([CH:35]([CH3:36])[CH3:37])[CH2:38][CH3:39])([CH3:40])[CH3:41].[NH2:19][NH2:20]>>[CH:1]1([O:7][NH:8][S:29]([c:26]2[cH:25][cH:24][c:23]([O:22][CH3:21])[cH:28][cH:27]2)(=[O:30])=[O:31])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

6

Reactant 5

HCID 74014-Methoxybenzenesulfonyl chlorideHCID 8028TetrahydrofuranHCID 9321HydrazineHCID 81531DiisopropylethylamineHCID 10467039N-cyclohexyloxyphthalimide

Product 1

HCID 22997164N1-(cyclohexyloxy)-4-methoxy-1-benzenesulfonamide

Sources & evidence

ORD record
ord-bcb146ba737d412693bf009c46b7cab7
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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