Dimethylformamide → 3-[5-Hydroxy-2-(4-hydroxy-phenyl)-benzofuran-7-yl]-acrylonitrile

HRID 940841Notes

Reaction equation

HRID 940841 reaction equation
[O:23]=[CH:24][N:25]([CH3:26])[CH3:27].[OH:1][c:2]1[cH:3][c:4]([CH:18]=[CH:19][C:20](=[O:21])[NH2:22])[c:5]2[c:6]([cH:7][c:8](-[c:10]3[cH:11][cH:12][c:13]([OH:16])[cH:14][cH:15]3)[o:9]2)[cH:17]1.[P:28]([Cl:29])([Cl:30])([Cl:31])=[O:32]>>[OH:1][c:2]1[cH:3][c:4]([CH:18]=[CH:19][C:20]#[N:22])[c:5]2[c:6]([cH:7][c:8](-[c:10]3[cH:11][cH:12][c:13]([OH:16])[cH:14][cH:15]3)[o:9]2)[cH:17]1

Participants

4

Reactant 3

HCID 6228DimethylformamideHCID 24813Phosphorus oxychlorideHCID 688451963-[5-Hydroxy-2-(4-hydroxyphenyl)-benzofuran-7-yl]-acrylamide

Product 1

HCID 688406933-[5-Hydroxy-2-(4-hydroxy-phenyl)-benzofuran-7-yl]-acrylonitrile

Sources & evidence

ORD record
ord-b7121d5522b14ee1affbaf10820aec77
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…