Methane → N-[3-(4-amino-2-cyanophenoxy)phenyl]-2,2,2-trifluoroacetamide

HRID 940874Notes

Reaction equation

HRID 940874 reaction equation
[C:1](#[N:2])[c:3]1[c:4]([O:5][c:6]2[cH:7][c:8]([NH:12][C:13]([C:14]([F:15])([F:16])[F:17])=[O:18])[cH:9][cH:10][cH:11]2)[cH:19][cH:20][c:21]([N+:23]([O-:24])=[O:25])[cH:22]1.[C:33].[CH3:26][N:27]1[C:28](=[O:29])[CH2:30][CH2:31][CH2:32]1.[Pd:34]>>[C:1](#[N:2])[c:3]1[c:4]([O:5][c:6]2[cH:7][c:8]([NH:12][C:13]([C:14]([F:15])([F:16])[F:17])=[O:18])[cH:9][cH:10][cH:11]2)[cH:19][cH:20][c:21]([NH2:23])[cH:22]1

Participants

5

Reactant 4

HCID 297MethaneHCID 13387N-methyl-2-pyrrolidoneHCID 23938PalladiumHCID 86644681N-[3-(2-cyano-4-nitrophenoxy)phenyl]-2,2,2-trifluoroacetamide

Product 1

HCID 86644682N-[3-(4-amino-2-cyanophenoxy)phenyl]-2,2,2-trifluoroacetamide

Sources & evidence

ORD record
ord-d9a489d3028340f4b0baa3b1771b468f
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…