Methanol → HCID 58883455, compound

HRID 940985Notes

Reaction equation

HRID 940985 reaction equation
[CH3:42][OH:43].[CH:1]([CH3:2])([CH3:3])[O:4][C:5]([c:6]1[c:7]([CH2:26][N:27]([CH3:28])[CH:29]2[CH2:30][CH2:31]2)[cH:8][c:9]([C:12]#[C:13][c:14]2[cH:15][c:16]([F:25])[c:17]([CH2:20][C:21](=[O:22])[O:23][CH3:24])[cH:18][cH:19]2)[cH:10][cH:11]1)=[O:32].[Li+:41].[O:33]1[CH2:34][CH2:35][CH2:36][CH2:37]1.[OH-:40].[OH2:38].[OH2:39]>>[CH:1]([CH3:2])([CH3:3])[O:4][C:5]([c:6]1[c:7]([CH2:26][N:27]([CH3:28])[CH:29]2[CH2:30][CH2:31]2)[cH:8][c:9]([C:12]#[C:13][c:14]2[cH:15][c:16]([F:25])[c:17]([CH2:20][C:21](=[O:22])[OH:23])[cH:18][cH:19]2)[cH:10][cH:11]1)=[O:32]

Participants

7

Reactant 6

HCID 887MethanolHCID 961HydroxideHCID 962Water2×HCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 690779862-[(Cyclopropyl-methyl-amino)-methyl]-4-(3-fluoro-4-methoxycarbonylmethyl-phenylethynyl)-benzoic acid isopropyl ester

Product 1

HCID 58883455HCID 58883455, compound

Sources & evidence

ORD record
ord-993cdc45011b48749e7f367033d60213
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…