Hydrogen Bromide → Ethyl 2-(2-aminothiazol-5-ylthio)acetate

HRID 942104Notes

Reaction equation

HRID 942104 reaction equation
[BrH:8].[C:16](=[O:17])([O-:18])[O-:19].[C:9]([CH2:10][SH:11])(=[O:12])[O:13][CH2:14][CH3:15].[K+:20].[K+:21].[NH2:1][c:2]1[s:3][c:4]([Br:7])[cH:5][n:6]1.[O:22]=[CH:23][N:24]([CH3:25])[CH3:26]>>[NH2:1][c:2]1[s:3][c:4]([S:11][CH2:10][C:9](=[O:12])[O:13][CH2:14][CH3:15])[cH:5][n:6]1

Participants

7

Reactant 6

HCID 260Hydrogen BromideHCID 813Potassium Cation2×HCID 6228DimethylformamideHCID 12185Ethyl ThioglycolateHCID 19660Carbonate IonHCID 436002-Thiazolamine, 5-bromo-

Product 1

HCID 21455623Ethyl 2-(2-aminothiazol-5-ylthio)acetate

Sources & evidence

ORD record
ord-aba5713cfa034331aa35c2409a0d81ac
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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