Isopropanol → N-(2-Cyano-indan-2-yl)-2-cyclobutoxy-3-methyl-benzamide

HRID 942299Notes

Reaction equation

HRID 942299 reaction equation
[CH:1]1([O:5][c:6]2[c:7]([C:8](=[O:9])[OH:10])[cH:11][cH:12][cH:13][c:14]2[CH3:15])[CH2:2][CH2:3][CH2:4]1.[CH:31]([N:32]([CH2:33][CH3:34])[CH:35]([CH3:36])[CH3:37])([CH3:38])[CH3:39].[CH:40]([OH:41])([CH3:42])[CH3:43].[Cl:16][CH2:17][Cl:18].[Cl:44][CH2:45][Cl:46].[NH2:19][C:20]1([C:29]#[N:30])[CH2:21][c:22]2[cH:23][cH:24][cH:25][cH:26][c:27]2[CH2:28]1>>[CH:1]1([O:5][c:6]2[c:7]([C:8](=[O:10])[NH:19][C:20]3([C:29]#[N:30])[CH2:21][c:22]4[cH:23][cH:24][cH:25][cH:26][c:27]4[CH2:28]3)[cH:11][cH:12][cH:13][c:14]2[CH3:15])[CH2:2][CH2:3][CH2:4]1

Participants

6

Reactant 5

HCID 3776IsopropanolHCID 6344Dichloromethane2×HCID 81531DiisopropylethylamineHCID 149899332-Amino-2,3-dihydro-1H-indene-2-carbonitrileHCID 593141552-Cyclobutyloxy-3-methylbenzoic acid

Product 1

HCID 59314349N-(2-Cyano-indan-2-yl)-2-cyclobutoxy-3-methyl-benzamide

Sources & evidence

ORD record
ord-2c6362feb8b6443cba96f21b9a24c1b2
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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