Formaldehyde → 2-(6-[N,N-bis(tert-butoxycarbonyl)amino]-5-methyl-pyridin-3-ylmethyl)-acrylic acid ethyl ester
Reaction equation
[CH2:1]([NH:2][CH2:3][CH3:4])[CH3:5].[CH2:38]=[O:39].[CH2:46]([Cl:47])[Cl:48].[CH2:6]([CH3:7])[O:8][C:9]([CH:10]([C:11]([OH:12])=[O:13])[CH2:14][c:15]1[cH:16][n:17][c:18]([N:22]([C:23](=[O:24])[O:25][C:26]([CH3:27])([CH3:28])[CH3:29])[C:30](=[O:31])[O:32][C:33]([CH3:34])([CH3:35])[CH3:36])[c:19]([CH3:21])[cH:20]1)=[O:37].[CH3:40][CH2:41][O:42][C:43](=[O:44])[CH3:45]>>[CH2:6]([CH3:7])[O:8][C:9]([C:10](=[CH2:11])[CH2:14][c:15]1[cH:16][n:17][c:18]([N:22]([C:23](=[O:24])[O:25][C:26]([CH3:27])([CH3:28])[CH3:29])[C:30](=[O:31])[O:32][C:33]([CH3:34])([CH3:35])[CH3:36])[c:19]([CH3:21])[cH:20]1)=[O:37]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-41eab2ad583e4811aa318b300a0262a4
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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