Hydrochloric Acid → Methyl 5-aminopyridine-3-carboxylate

HRID 942368Notes

Reaction equation

HRID 942368 reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:8][c:9]1[cH:10][c:11]([C:15](=[O:16])[O:17][CH3:18])[cH:12][n:13][cH:14]1)([CH3:5])([CH3:6])[CH3:7].[C:26](=[O:27])([O-:28])[O-:29].[CH3:20][CH2:21][O:22][C:23](=[O:24])[CH3:25].[CH3:32][OH:33].[ClH:19].[K+:30].[K+:31].[OH2:34]>>[NH2:8][c:9]1[cH:10][c:11]([C:15](=[O:16])[O:17][CH3:18])[cH:12][n:13][cH:14]1

Participants

8

Reactant 7

HCID 313Hydrochloric AcidHCID 813Potassium Cation2×HCID 887MethanolHCID 962WaterHCID 8857Ethyl AcetateHCID 19660Carbonate IonHCID 18945232Methyl 5-(tert-butoxycarbonylamino)nicotinate

Product 1

HCID 1514432Methyl 5-aminopyridine-3-carboxylate

Sources & evidence

ORD record
ord-7c07f6fc26874796a5daaec61df4c85a
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…