Dimethylformamide → N-[1-[1-(4-fluorophenyl)indazol-5-yl]oxy-1-phenylpropan-2-yl]-5-methyl-1,3,4-oxadiazole-2-carboxamide

HRID 94262Notes

Reaction equation

HRID 94262 reaction equation
[CH2:25]([N:26]([CH:27]([CH3:28])[CH3:29])[CH:30]([CH3:31])[CH3:32])[CH3:33].[CH3:35][c:36]1[n:37][n:38][c:39]([C:41](=[O:42])[OH:43])[o:40]1.[Cl:76][CH2:77][Cl:78].[F:44][c:45]1[cH:46][cH:47][c:48](-[n:51]2[n:52][cH:53][c:54]3[cH:55][c:56]([O:60][CH:61]([CH:62]([CH3:63])[NH2:64])[c:65]4[cH:66][cH:67][cH:68][cH:69][cH:70]4)[cH:57][cH:58][c:59]23)[cH:49][cH:50]1.[K:34].[O:71]=[CH:72][N:73]([CH3:74])[CH3:75].[P-:1]([F:2])([F:3])([F:4])([F:5])([F:6])[F:7].[n:8]1([O:9][C:10]([N:11]([CH3:12])[CH3:13])=[N+:14]([CH3:15])[CH3:16])[c:17]2[n:18][cH:19][cH:20][cH:21][c:22]2[n:23][n:24]1>>[CH3:35][c:36]1[n:37][n:38][c:39]([C:41](=[O:43])[NH:64][CH:62]([CH:61]([O:60][c:56]2[cH:55][c:54]3[cH:53][n:52][n:51](-[c:48]4[cH:47][cH:46][c:45]([F:44])[cH:50][cH:49]4)[c:59]3[cH:58][cH:57]2)[c:65]2[cH:66][cH:67][cH:68][cH:69][cH:70]2)[CH3:63])[o:40]1

Participants

9

Reactant 8

HCID 6228DimethylformamideHCID 6344DichloromethaneHCID 9886HexafluorophosphateHCID 81531DiisopropylethylamineHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 5462222PotassiumHCID 198119465-Methyl-1,3,4-oxadiazole-2-carboxylic acidHCID 722587151-[1-(4-Fluorophenyl)indazol-5-yl]oxy-1-phenylpropan-2-amine

Product 1

HCID 72258651N-[1-[1-(4-fluorophenyl)indazol-5-yl]oxy-1-phenylpropan-2-yl]-5-methyl-1,3,4-oxadiazole-2-carboxamide

Sources & evidence

ORD record
ord-c046f310e9434584a65bca8a0047d0ec
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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