Tetrahydrofuran → 4-(4-Fluorophenoxy)benzene-1-thiol

HRID 942668Notes

Reaction equation

HRID 942668 reaction equation
[Al+3:2].[F:7][c:8]1[cH:9][cH:10][c:11]([O:12][c:13]2[cH:14][cH:15][c:16]([S:19]([Cl:20])(=[O:21])=[O:22])[cH:17][cH:18]2)[cH:23][cH:24]1.[H-:1].[H-:4].[H-:5].[H-:6].[Li+:3].[O:25]1[CH2:26][CH2:27][CH2:28][CH2:29]1>>[F:7][c:8]1[cH:9][cH:10][c:11]([O:12][c:13]2[cH:14][cH:15][c:16]([SH:19])[cH:17][cH:18]2)[cH:23][cH:24]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 104727Aluminum CationHCID 166653Hydride4×HCID 27827574-(4-Fluorophenoxy)benzenesulphonyl chloride

Product 1

HCID 217055854-(4-Fluorophenoxy)benzene-1-thiol

Sources & evidence

ORD record
ord-128b8d790dc0437c83e4c6f9d7aada6f
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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