Chloride → 1-benzyl-1-hydroxy-6-methoxy-3-phenyl-1H-indene-2-carboxylic acid ethyl ester

HRID 942909Notes

Reaction equation

HRID 942909 reaction equation
[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[C:6]1=[C:14]([c:15]2[cH:16][cH:17][cH:18][cH:19][cH:20]2)[c:13]2[c:8]([cH:9][c:10]([O:21][CH3:22])[cH:11][cH:12]2)[C:7]1=[O:23].[CH2:25]([c:26]1[cH:27][cH:28][cH:29][cH:30][cH:31]1)[Mg+:32].[CH2:33]1[O:34][CH2:35][CH2:36][CH2:37]1.[Cl-:24]>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[C:6]1=[C:14]([c:15]2[cH:16][cH:17][cH:18][cH:19][cH:20]2)[c:13]2[c:8]([cH:9][c:10]([O:21][CH3:22])[cH:11][cH:12]2)[C:7]1([OH:23])[CH2:25][c:26]1[cH:27][cH:28][cH:29][cH:30][cH:31]1

Participants

5

Reactant 4

HCID 312ChlorideHCID 8028TetrahydrofuranHCID 23249734Ethyl 6-methoxy-1-oxo-3-phenyl-1H-indene-2-carboxylateHCID 178507042HCID 178507042, compound

Product 1

HCID 115675291-benzyl-1-hydroxy-6-methoxy-3-phenyl-1H-indene-2-carboxylic acid ethyl ester

Sources & evidence

ORD record
ord-9d0ee51f07ca466f80f7f20cf009c2ad
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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