Diethyl Ether → 1,1,1-Trifluoro-2-trifluoromethyl-2-hydroxy-5-pentyl methacrylate
Reaction equation
[C:20]([C:21](=[CH2:22])[CH3:23])(=[O:24])[Cl:25].[CH2:1]([Li:2])[CH2:3][CH2:4][CH3:5].[CH2:26]1[O:27][CH2:28][CH2:29][CH2:30]1.[CH3:31][CH2:32][O:33][CH2:34][CH3:35].[F:6][C:7]([C:8]([CH2:9][CH2:10][CH2:11][OH:12])([OH:13])[C:14]([F:15])([F:16])[F:17])([F:18])[F:19]>>[F:6][C:7]([C:8]([CH2:9][CH2:10][CH2:11][O:12][C:20]([C:21](=[CH2:22])[CH3:23])=[O:24])([OH:13])[C:14]([F:15])([F:16])[F:17])([F:18])[F:19]Participants
6
Sources & evidence
- ORD record
- ord-1abaa063b00f45ee8c870363c282484d
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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