Hydrochloric Acid → 3-(4,4-Diphenylpiperidin-1-yl)propionitrile

HRID 943350Notes

Reaction equation

HRID 943350 reaction equation
[CH2:27]=[CH:28][C:29]#[N:30].[CH3:20][CH2:21][N:22]([CH2:23][CH3:24])[CH2:25][CH3:26].[CH3:31][CH2:32][OH:33].[ClH:1].[c:2]1([C:8]2([c:14]3[cH:15][cH:16][cH:17][cH:18][cH:19]3)[CH2:9][CH2:10][NH:11][CH2:12][CH2:13]2)[cH:3][cH:4][cH:5][cH:6][cH:7]1>>[c:2]1([C:8]2([c:14]3[cH:15][cH:16][cH:17][cH:18][cH:19]3)[CH2:9][CH2:10][N:11]([CH2:27][CH2:28][C:29]#[N:30])[CH2:12][CH2:13]2)[cH:3][cH:4][cH:5][cH:6][cH:7]1

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 702EthanolHCID 7855AcrylonitrileHCID 8471TriethylamineHCID 28232394,4-Diphenylpiperidine

Product 1

HCID 155128643-(4,4-Diphenylpiperidin-1-yl)propionitrile

Sources & evidence

ORD record
ord-dbccc76f48204575b9e1635448d06a4e
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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