HRID943613

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID769

Bicarbonate Ion

CHO3-

HCID923

Sodium ion

Na+

HCID7679

Benzeneacetyl chloride

C8H7ClO

HCID8028

Tetrahydrofuran

C4H8O

HCID8471

Triethylamine

C6H15N

结构：CCc1nc(-c2cccc(C)c2)c(-c2ccnc(N)c2)s1

HCID9857349

4-[2-ethyl-4-(3-methylphenyl)-1,3-thiazol-5-yl]pyridin-2-amine

C17H17N3S

PRODUCTS

生成物

结构：CCc1nc(-c2cccc(C)c2)c(-c2ccnc(NC(=O)Cc3ccccc3)c2)s1

HCID10295235

N-[4-[2-ETHYL-4-(3-METHYLPHENYL)-1,3-THIAZOL-5-YL]-2-PYRIDYL]PHENYLACETAMIDE

C25H23N3OS

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-62bd8958e73d49d38dcb6098bbcce3db
来源数据集: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D
来源说明: Validation data from https://doi.org/10.1039/C8SC04228D

反应 SMILES

[C:39](=[O:40])([O-:41])[OH:42].[CH2:1]([CH3:2])[c:3]1[s:4][c:5](-[c:15]2[cH:16][c:17]([NH2:21])[n:18][cH:19][cH:20]2)[c:6](-[c:8]2[cH:9][c:10]([CH3:14])[cH:11][cH:12][cH:13]2)[n:7]1.[CH3:32][CH2:33][N:34]([CH2:35][CH3:36])[CH2:37][CH3:38].[Na+:43].[O:44]1[CH2:45][CH2:46][CH2:47][CH2:48]1.[c:22]1([CH2:28][C:29](=[O:30])[Cl:31])[cH:23][cH:24][cH:25][cH:26][cH:27]1>>[CH2:1]([CH3:2])[c:3]1[s:4][c:5](-[c:15]2[cH:16][c:17]([NH:21][C:29]([CH2:28][c:22]3[cH:23][cH:24][cH:25][cH:26][cH:27]3)=[O:30])[n:18][cH:19][cH:20]2)[c:6](-[c:8]2[cH:9][c:10]([CH3:14])[cH:11][cH:12][cH:13]2)[n:7]1