Ammonium → 1-(3-Bromo-5-ethoxy-phenyl)-pyrrolidine

HRID 943740Notes

Reaction equation

HRID 943740 reaction equation
[Br:1][c:2]1[cH:3][c:4]([N:12]2[CH2:13][CH2:14][CH2:15][CH2:16]2)[cH:5][c:6]([O:8][CH2:9][O:10][CH3:11])[cH:7]1.[CH2:25]([I:26])[CH3:27].[CH2:28]([Cl:29])[Cl:30].[CH3:31][OH:32].[K+:19].[K+:20].[NH4+:17].[O-:21][C:22]([O-:23])=[O:24].[O:33]=[CH:34][N:35]([CH3:36])[CH3:37].[OH-:18]>>[Br:1][c:2]1[cH:3][c:4]([N:12]2[CH2:13][CH2:14][CH2:15][CH2:16]2)[cH:5][c:6]([O:8][CH2:9][CH3:22])[cH:7]1

Participants

10

Reactant 9

HCID 223AmmoniumHCID 813Potassium Cation2×HCID 887MethanolHCID 961HydroxideHCID 6228DimethylformamideHCID 6340IodoethaneHCID 6344DichloromethaneHCID 19660Carbonate IonHCID 595410311-(3-Bromo-5-methoxymethoxy-phenyl)-pyrrolidine

Product 1

HCID 595408171-(3-Bromo-5-ethoxy-phenyl)-pyrrolidine

Sources & evidence

ORD record
ord-89130e680669489ea1a9dc61b48f5585
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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