HRID944453

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID176

Acetic Acid

C2H4O2

HCID6228

N,N-Dimethylformamide

C3H7NO

HCID12286

3-Bromopyridine

C5H4BrN

HCID23978

Copper

HCID5462222

Potassium

结构：COc1ccc(C(C(N)=O)(C(C)C)N2C(=O)C(NC(=O)c3cc4ccccc4[nH]3)C(=O)Nc3ccccc32)cc1

HCID86752409

未命名化合物

PRODUCTS

生成物

结构：COc1ccc(C(C(N)=O)(C(C)C)N2C(=O)C(NC(=O)c3cc4ccccc4[nH]3)C(=O)N(c3cccnc3)c3ccccc32)cc1

HCID86752408

未命名化合物

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-a47e3435375741a698d519582429ae3d
来源数据集: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D
来源说明: Validation data from https://doi.org/10.1039/C8SC04228D

反应 SMILES

[Br:41][c:42]1[cH:43][n:44][cH:45][cH:46][cH:47]1.[C:49]([OH:50])(=[O:51])[CH3:52].[CH:1]([CH3:2])([CH3:3])[C:4]([N:5]1[c:6]2[c:7]([cH:26][cH:27][cH:28][cH:29]2)[NH:8][C:9](=[O:25])[CH:10]([NH:13][C:14](=[O:15])[c:16]2[nH:17][c:18]3[cH:19][cH:20][cH:21][cH:22][c:23]3[cH:24]2)[C:11]1=[O:12])([C:30]([NH2:31])=[O:32])[c:33]1[cH:34][cH:35][c:36]([O:39][CH3:40])[cH:37][cH:38]1.[Cu:53].[K:48].[O:54]=[CH:55][N:56]([CH3:57])[CH3:58]>>[CH:1]([CH3:2])([CH3:3])[C:4]([N:5]1[c:6]2[c:7]([cH:26][cH:27][cH:28][cH:29]2)[N:8]([c:42]2[cH:43][n:44][cH:45][cH:46][cH:47]2)[C:9](=[O:25])[CH:10]([NH:13][C:14](=[O:15])[c:16]2[nH:17][c:18]3[cH:19][cH:20][cH:21][cH:22][c:23]3[cH:24]2)[C:11]1=[O:12])([C:30]([NH2:31])=[O:32])[c:33]1[cH:34][cH:35][c:36]([O:39][CH3:40])[cH:37][cH:38]1