Acetonitrile → 6-(Benzyloxy)-2-chlorobenzo[d]thiazole

HRID 944591Notes

Reaction equation

HRID 944591 reaction equation
[Br:1][CH2:2][c:3]1[cH:4][cH:5][cH:6][cH:7][cH:8]1.[C:20](=[O:21])([O-:22])[O-:23].[CH3:26][C:27]#[N:28].[CH3:29][CH2:30][O:31][C:32]([CH3:33])=[O:34].[Cl:9][c:10]1[s:11][c:12]2[c:13]([n:14]1)[cH:15][cH:16][c:17]([OH:19])[cH:18]2.[Cs+:24].[Cs+:25]>>[CH2:2]([c:3]1[cH:4][cH:5][cH:6][cH:7][cH:8]1)[O:19][c:17]1[cH:16][cH:15][c:13]2[c:12]([s:11][c:10]([Cl:9])[n:14]2)[cH:18]1

Participants

7

Reactant 6

HCID 6342AcetonitrileHCID 7498Benzyl BromideHCID 8857Ethyl AcetateHCID 19660Carbonate IonHCID 104967Cesium cation2×HCID 147498432-Chlorobenzo[d]thiazol-6-ol

Product 1

HCID 596715856-(Benzyloxy)-2-chlorobenzo[d]thiazole

Sources & evidence

ORD record
ord-a1a5df38b2aa4475a9749e5cf0cf49c3
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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