Benzaldehyde → 1-isopropyl-4-phenyl-3,4,6,7-tetrahydro-furo[3,2-g] quinazolin-2(1H)-one

HRID 944689Notes

Reaction equation

HRID 944689 reaction equation
[CH3:25][S:26](=[O:27])(=[O:28])[OH:29].[CH3:30][c:31]1[cH:32][cH:33][cH:34][cH:35][cH:36]1.[CH:17](=[O:18])[c:19]1[cH:20][cH:21][cH:22][cH:23][cH:24]1.[CH:1]([CH3:2])([CH3:3])[N:4]([C:5](=[O:6])[NH2:7])[c:8]1[cH:9][c:10]2[c:11]([cH:15][cH:16]1)[CH2:12][CH2:13][O:14]2>>[CH:1]([CH3:2])([CH3:3])[N:4]1[C:5](=[O:6])[NH:7][CH:17]([c:19]2[cH:20][cH:21][cH:22][cH:23][cH:24]2)[c:16]2[c:8]1[cH:9][c:10]1[c:11]([cH:15]2)[CH2:12][CH2:13][O:14]1

Participants

5

Reactant 4

HCID 240BenzaldehydeHCID 1140TolueneHCID 6395Methanesulfonic AcidHCID 21528985N-(2,3-Dihydro-1-benzofuran-6-yl)-N-propan-2-ylurea

Product 1

HCID 215289561-isopropyl-4-phenyl-3,4,6,7-tetrahydro-furo[3,2-g] quinazolin-2(1H)-one

Sources & evidence

ORD record
ord-18084fb03d2945298e35c767704b9428
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…