Toluene → Hydrochloric Acid

HRID 944762Notes

Reaction equation

HRID 944762 reaction equation
[CH3:1][O:2][CH2:3][C:4]1([NH:18][c:19]2[cH:20][cH:21][cH:22][cH:23][cH:24]2)[CH2:5][CH2:6][N:7]([CH2:10][CH2:11][c:12]2[cH:13][cH:14][cH:15][cH:16][cH:17]2)[CH2:8][CH2:9]1.[CH3:31][c:32]1[cH:33][cH:34][cH:35][cH:36][cH:37]1.[CH:25]1([C:28](=[O:29])[Cl:30])[CH2:26][CH2:27]1>>[CH3:1][O:2][CH2:3][C:4]1([N:18]([c:19]2[cH:20][cH:21][cH:22][cH:23][cH:24]2)[C:28]([CH:25]2[CH2:26][CH2:27]2)=[O:29])[CH2:5][CH2:6][N:7]([CH2:10][CH2:11][c:12]2[cH:13][cH:14][cH:15][cH:16][cH:17]2)[CH2:8][CH2:9]1.[ClH:30]

Participants

5

Reactant 3

HCID 1140TolueneHCID 77637Cyclopropanecarbonyl chlorideHCID 122982104-Piperidinamine, 4-(methoxymethyl)-N-phenyl-1-(2-phenylethyl)-

Product 2

HCID 313Hydrochloric AcidHCID 12298132N-[4-(methoxymethyl)-1-(2-phenylethyl)piperidin-4-yl]-N-phenylcyclopropanecarboxamide

Sources & evidence

ORD record
ord-157916a2fba04deebaed6aa1bb8ed42d
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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