Hydroxide → 4-(2-Amino-4-methylphenoxy)-6,7-dimethoxyquinoline

HRID 944820Notes

Reaction equation

HRID 944820 reaction equation
[CH2:33]([N:34]([CH2:35][CH3:36])[CH2:37][CH3:38])[CH3:39].[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:6]([O:15][c:16]3[c:17]([N+:23]([O-:24])=[O:25])[cH:18][c:19]([CH3:22])[cH:20][cH:21]3)[cH:7][cH:8][n:9][c:10]2[cH:11][c:12]1[O:13][CH3:14].[CH3:28][N:29]([CH3:30])[CH:31]=[O:32].[H:26][H:27].[OH-:40].[OH-:42].[Pd+2:41]>>[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:6]([O:15][c:16]3[c:17]([NH2:23])[cH:18][c:19]([CH3:22])[cH:20][cH:21]3)[cH:7][cH:8][n:9][c:10]2[cH:11][c:12]1[O:13][CH3:14]

Participants

7

Reactant 6

HCID 961Hydroxide2×HCID 6228DimethylformamideHCID 8471TriethylamineHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 230784026,7-Dimethoxy-4-(4-methyl-2-nitrophenoxy)quinolineHCID 178418361HCID 178418361, compound

Product 1

HCID 230785874-(2-Amino-4-methylphenoxy)-6,7-dimethoxyquinoline

Sources & evidence

ORD record
ord-033be93268cc48b2be949a3b153a7225
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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