Water → ethyl 4-(5-chloropyrazin-2-yl)-2-[4-[(3,4-dichloro-5-methyl-1H-pyrrole-2-carbonyl)amino]-3-ethoxypiperidin-1-yl]-1,3-thiazole-5-carboxylate
Reaction equation
[Br:21][c:22]1[s:23][c:24]([C:34](=[O:35])[O:36][CH2:37][CH3:38])[c:25](-[c:27]2[n:28][cH:29][c:30]([Cl:33])[n:31][cH:32]2)[n:26]1.[CH3:49][N:50]1[CH2:51][CH2:52][CH2:53][CH2:54]1.[CH:39]([N:40]([CH2:41][CH3:42])[CH:43]([CH3:44])[CH3:45])([CH3:46])[CH3:47].[Cl:1][c:2]1[c:3]([C:9](=[O:10])[NH:11][CH:12]2[CH:13]([O:18][CH2:19][CH3:20])[CH2:14][NH:15][CH2:16][CH2:17]2)[nH:4][c:5]([CH3:8])[c:6]1[Cl:7].[OH2:48]>>[Cl:1][c:2]1[c:3]([C:9](=[O:10])[NH:11][CH:12]2[CH:13]([O:18][CH2:19][CH3:20])[CH2:14][N:15]([c:22]3[s:23][c:24]([C:34](=[O:35])[O:36][CH2:37][CH3:38])[c:25](-[c:27]4[n:28][cH:29][c:30]([Cl:33])[n:31][cH:32]4)[n:26]3)[CH2:16][CH2:17]2)[nH:4][c:5]([CH3:8])[c:6]1[Cl:7]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-0562ef8a7c0b4f8e85c26621aa4021cb
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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