Hydrochloric Acid → Hydrochloric Acid

HRID 945471Notes

Reaction equation

HRID 945471 reaction equation
[CH2:2]([c:3]1[cH:4][cH:5][cH:6][cH:7][cH:8]1)[O:9][c:10]1[c:11]([O:21][CH3:22])[cH:12][c:13]2[c:14]([Cl:20])[n:15][cH:16][n:17][c:18]2[cH:19]1.[CH:37]([OH:38])([CH3:39])[CH3:40].[ClH:1].[F:23][c:24]1[c:25]([NH2:26])[cH:27][c:28]([O:32][C:33](=[O:34])[O:35][CH3:36])[c:29]([CH3:31])[cH:30]1>>[CH2:2]([c:3]1[cH:4][cH:5][cH:6][cH:7][cH:8]1)[O:9][c:10]1[c:11]([O:21][CH3:22])[cH:12][c:13]2[c:14]([NH:26][c:25]3[c:24]([F:23])[cH:30][c:29]([CH3:31])[c:28]([O:32][C:33](=[O:34])[O:35][CH3:36])[cH:27]3)[n:15][cH:16][n:17][c:18]2[cH:19]1.[ClH:20]

Participants

6

Reactant 4

HCID 313Hydrochloric AcidHCID 3776IsopropanolHCID 106619987-(Benzyloxy)-4-chloro-6-methoxyquinazolineHCID 226250465-Amino-4-fluoro-2-methylphenyl Methoxyformate

Product 2

HCID 313Hydrochloric AcidHCID 226249317-Benzyloxy-4-(2-fluoro-5-methoxycarbonyloxy-4-methylanilino)-6-methoxyquinazoline

Sources & evidence

ORD record
ord-d7e9a74c109e48948de28d7a6f296b15
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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