Chloride → N-acetyl-4-(4-n-propylphenyl)-piperidine

HRID 945577Notes

Reaction equation

HRID 945577 reaction equation
[C:17]([OH:18])(=[O:19])[CH2:20][CH3:21].[C:1]([N:2]1[CH2:3][CH2:4][CH:5]([c:6]2[cH:7][cH:8][cH:9][cH:10][cH:11]2)[CH2:12][CH2:13]1)(=[O:14])[CH3:15].[C:26]([CH3:27])(=[O:28])[N:29]1[CH2:30][CH2:31][CH:32]([c:35]2[cH:36][cH:37][c:38]([C:41]([CH2:42][CH3:43])=[O:44])[cH:39][cH:40]2)[CH2:33][CH2:34]1.[Cl-:16].[Cl:22][Al:23]([Cl:24])[Cl:25]>>[C:26]([CH3:27])(=[O:28])[N:29]1[CH2:30][CH2:31][CH:32]([c:35]2[cH:36][cH:37][c:38]([CH2:41][CH2:42][CH3:43])[cH:39][cH:40]2)[CH2:33][CH2:34]1

Participants

6

Reactant 5

HCID 312ChlorideHCID 1032Propionic AcidHCID 24012Aluminum ChlorideHCID 11608128HCID 11608128, compoundHCID 13151836N-acetyl-4-(4-propionylphenyl)-piperidine

Product 1

HCID 13151837N-acetyl-4-(4-n-propylphenyl)-piperidine

Sources & evidence

ORD record
ord-072a90430e9044f8b8a7340175c1ee27
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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