Tetrahydrofuran → 4-fluoro-N-[4-imidazol-1-yl-3-(trifluoromethyl)phenyl]-3-[4-[(6-methoxypyridin-3-yl)amino]-2-oxo-4-sulfanylidenebutoxy]benzamide

HRID 945932Notes

Reaction equation

[CH2:54]1[O:55][CH2:56][CH2:57][CH2:58]1.[CH3:14][CH:15]([N-:16][CH:17]([CH3:18])[CH3:19])[CH3:20].[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([NH:9][C:10]([CH3:11])=[S:12])[cH:7][n:8]1.[F:21][c:22]1[c:23]([O:46][CH2:47][C:48]([N:49]([O:50][CH3:51])[CH3:52])=[O:53])[cH:24][c:25]([C:26](=[O:27])[NH:28][c:29]2[cH:30][c:31]([C:40]([F:41])([F:42])[F:43])[c:32](-[n:35]3[cH:36][n:37][cH:38][cH:39]3)[cH:33][cH:34]2)[cH:44][cH:45]1.[Li+:13]>>[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([NH:9][C:10]([CH2:11][C:48]([CH2:47][O:46][c:23]2[c:22]([F:21])[cH:45][cH:44][c:25]([C:26](=[O:27])[NH:28][c:29]3[cH:30][c:31]([C:40]([F:41])([F:42])[F:43])[c:32](-[n:35]4[cH:36][n:37][cH:38][cH:39]4)[cH:33][cH:34]3)[cH:24]2)=[O:53])=[S:12])[cH:7][n:8]1