Dimethylformamide → 1-Boc-3-cyanopyrrolidine

HRID 94606Notes

Reaction equation

HRID 94606 reaction equation
[Cl:1][c:2]1[n:3][c:4]([Cl:5])[n:6][c:7]([Cl:8])[n:9]1.[NH2:10][C:11](=[O:12])[CH:13]1[CH2:14][N:15]([C:18](=[O:19])[O:20][C:21]([CH3:22])([CH3:23])[CH3:24])[CH2:16][CH2:17]1.[O:25]=[CH:26][N:27]([CH3:28])[CH3:29]>>[N:10]#[C:11][CH:13]1[CH2:14][N:15]([C:18](=[O:19])[O:20][C:21]([CH3:22])([CH3:23])[CH3:24])[CH2:16][CH2:17]1

Participants

4

Reactant 3

HCID 6228DimethylformamideHCID 7954Cyanuric chlorideHCID 4571096Tert-butyl 3-carbamoylpyrrolidine-1-carboxylate

Product 1

HCID 27567871-Boc-3-cyanopyrrolidine

Sources & evidence

ORD record
ord-2705d44f89fb481a82acf65deff1b97d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

Loading…