Chloride → 4-Chloro-N-[5-chloro-2-(1H-pyrazolo[3,4-b]pyridine-4-carbonyl)-pyridin-3-yl]-3-trifluoromethyl-benzenesulfonamide

HRID 946305Notes

Reaction equation

HRID 946305 reaction equation
[CH2:44]1[O:45][CH2:46][CH2:47][CH2:48]1.[CH3:16][O:17][N:18]([C:19](=[O:20])[c:21]1[n:22][cH:23][c:24]([Cl:42])[cH:25][c:26]1[NH:27][S:28](=[O:29])(=[O:30])[c:31]1[cH:32][c:33]([C:38]([F:39])([F:40])[F:41])[c:34]([Cl:37])[cH:35][cH:36]1)[CH3:43].[CH:12]([Mg+:13])([CH3:14])[CH3:15].[Cl-:11].[I:1][c:2]1[c:3]2[cH:4][n:5][nH:6][c:7]2[n:8][cH:9][cH:10]1>>[c:2]1([C:19](=[O:20])[c:21]2[n:22][cH:23][c:24]([Cl:42])[cH:25][c:26]2[NH:27][S:28](=[O:29])(=[O:30])[c:31]2[cH:32][c:33]([C:38]([F:39])([F:40])[F:41])[c:34]([Cl:37])[cH:35][cH:36]2)[c:3]2[cH:4][n:5][nH:6][c:7]2[n:8][cH:9][cH:10]1

Participants

6

Reactant 5

HCID 312ChlorideHCID 8028TetrahydrofuranHCID 576428014-Iodo-1H-pyrazolo[3,4-b]pyridineHCID 579421055-Chloro-3-(4-chloro-3-trifluoromethyl-benzenesulfonylamino)-pyridine-2-carboxylic acid methoxy-methyl-amideHCID 178461726HCID 178461726, compound

Product 1

HCID 441775994-Chloro-N-[5-chloro-2-(1H-pyrazolo[3,4-b]pyridine-4-carbonyl)-pyridin-3-yl]-3-trifluoromethyl-benzenesulfonamide

Sources & evidence

ORD record
ord-35c118e2d877484395ba07e956de76e5
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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