Sodium ion → 2-(2-(4-Fluoro-benzyl)-5-(5-chloro-2-(methylthio)pyrimidin-4-yl)thiophen-3-yl)ethanol
Reaction equation
[CH2:1]([Li:2])[CH2:3][CH2:4][CH3:5].[Cl:22][c:23]1[cH:24][n:25][c:26]([S:29][CH3:30])[n:27][cH:28]1.[Cl:31][C:32]1=[C:43]([Cl:44])[C:41](=[O:42])[C:38]([C:39]#[N:40])=[C:35]([C:36]#[N:37])[C:33]1=[O:34].[F:6][c:7]1[cH:8][cH:9][c:10]([CH2:11][c:12]2[s:13][cH:14][cH:15][c:16]2[CH2:17][CH2:18][OH:19])[cH:20][cH:21]1.[Na+:46].[O:47]1[CH2:48][CH2:49][CH2:50][CH2:51]1.[OH-:45].[OH2:52]>>[F:6][c:7]1[cH:8][cH:9][c:10]([CH2:11][c:12]2[s:13][c:14](-[c:24]3[c:23]([Cl:22])[cH:28][n:27][c:26]([S:29][CH3:30])[n:25]3)[cH:15][c:16]2[CH2:17][CH2:18][OH:19])[cH:20][cH:21]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-e546e46cc47c423eb2056c57a5327799
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
Loading…