Ethyl Acetate → Chloride

HRID 946532Notes

Reaction equation

HRID 946532 reaction equation
[CH3:37][CH2:38][O:39][C:40](=[O:41])[CH3:42].[Cl:28][CH2:29][C:30](=[O:31])[c:32]1[s:33][cH:34][cH:35][cH:36]1.[N:1]12[CH2:2][CH:3]([O:9][C:10]([CH:11]([c:12]3[cH:13][cH:14][cH:15][cH:16][cH:17]3)[N:18]([CH3:19])[c:20]3[cH:21][cH:22][c:23]([F:26])[cH:24][cH:25]3)=[O:27])[CH:4]([CH2:5][CH2:6]1)[CH2:7][CH2:8]2>>[Cl-:28].[N+:1]12([CH2:29][C:30](=[O:31])[c:32]3[s:33][cH:34][cH:35][cH:36]3)[CH2:2][CH:3]([O:9][C:10]([CH:11]([c:12]3[cH:13][cH:14][cH:15][cH:16][cH:17]3)[N:18]([CH3:19])[c:20]3[cH:21][cH:22][c:23]([F:26])[cH:24][cH:25]3)=[O:27])[CH:4]([CH2:5][CH2:6]1)[CH2:7][CH2:8]2

Participants

5

Reactant 3

HCID 8857Ethyl AcetateHCID 27579252-(Chloroacetyl)thiopheneHCID 671248351-azabicyclo[2.2.2]octan-3-yl 2-(4-fluoro-N-methylanilino)-2-phenylacetate

Product 2

HCID 312ChlorideHCID 178482183HCID 178482183, compound

Sources & evidence

ORD record
ord-324528ac8661453391217ebbbc66860b
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…